The quality of the debridement is the most critical factor in successful management of osteomyelitis, but filling the dead space left behind by removal of bone is essential to reduce the risk of recurrence, and the formation of new host bone is critical to reducing the risk of recurrence and fracture.
In a study published by the Oxford Bone Infection Unit, 100 patients with chronic osteomyelitis treated by single-stage surgery and implantation of CERAMENT|G had a 96% eradication of infection at one year. In a comparative study of three different absorbable antibiotic carriers at the same centre, the fracture rate for CERAMENT was half that of the other carriers evaluated.
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488. PR 0488-01 en EU McNally et al. A comparative study of three resorbable antibiotic carriers.
McNally et al. Single-stage treatment of chronic osteomyelitis with a new absorbable gentamicin loaded CaS-HA - first 100 cases, Bone Joint J 2016;98-B:1289–96.